Von Willebrand Disease
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Rapid Warfarin Reversal
Congenital Fibrinogen Deficiency
People with von Willebrand disease (VWD) have a problem with one of the clotting factors in the blood; this particular clotting factor is known as von Willebrand factor.
In people unaffected by von Willebrand disease, this clotting factor helps platelets stick to the wall of the damaged blood vessel and assists the glue-like clotting.
As well as having problems with their von Willebrand clotting factor, many people with von Willebrand disease also have a reduced level of another type of blood clotting agent, factor VIII. This is the clotting factor missing in people with haemophilia A.
Symptoms of von Willebrand disease
Symptoms of VWD vary. Some people with von Willebrand disease never suffer any symptoms, but those who do may experience recurrent nosebleeds, easy bruising, bleeding from the mouth or gums and, in women, heavy periods. People with VWD may also bleed excessively after injury or surgery, and, in very rare cases, bleeding may occur in joints or muscles.
For further information on haemophilia, you can visit The Haemophilia Society website at:
UK/CORP/11-0061ak Date of preparation: Dec 2011